Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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tolQTolQ protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. (233 aa)    
Predicted Functional Partners:
tolR
TolR protein; Identified by similarity to SP:P05829; match to protein family HMM PF02472; match to protein family HMM TIGR02801.
 
 
 0.986
tolB
Tol-pal system beta propeller repeat protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
 
  
 0.973
ybgC
Tol-pal system-associated acyl-CoA thioesterase; Identified by match to protein family HMM PF03061; match to protein family HMM TIGR00051; match to protein family HMM TIGR02799.
 
  
 0.863
AFE_0486
Biopolymer transport protein, ExbD/TolR family; Identified by match to protein family HMM PF02472.
 
   0.850
ruvB
Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
       0.803
tolA
TolA protein; Identified by similarity to GB:CAB50780.1; match to protein family HMM TIGR01352; match to protein family HMM TIGR02794.
       0.773
bamA
Outer membrane protein, OMP85 family; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
     0.736
AFE_3004
Biopolymer transport protein, ExbD/TolR family; Identified by match to protein family HMM PF02472.
 
   0.724
ruvA
Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
 
     0.702
AFE_0769
Biopolymer transport protein, ExbD/TolR family; Identified by match to protein family HMM PF02472.
 
   0.702
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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