Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AFE_0073Undecaprenyl-phosphate galactosephosphotransferase; Identified by similarity to SP:P26406; match to protein family HMM PF02397; match to protein family HMM TIGR03022; match to protein family HMM TIGR03025. (488 aa)    
Predicted Functional Partners:
AFE_1340
Tyrosine-protein kinase, putative; Identified by similarity to SP:P38134; match to protein family HMM PF02706.
 
  
 0.923
AFE_1366
Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Identified by similarity to SP:P29956; match to protein family HMM PF00483; match to protein family HMM PF01050; match to protein family HMM PF07883; match to protein family HMM TIGR01479; Belongs to the mannose-6-phosphate isomerase type 2 family.
  
  
 0.854
AFE_2960
Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Identified by match to protein family HMM PF00483; match to protein family HMM PF01050; match to protein family HMM PF07883; match to protein family HMM TIGR01479; Belongs to the mannose-6-phosphate isomerase type 2 family.
  
  
 0.854
AFE_3293
Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Identified by similarity to SP:P29956; match to protein family HMM PF00483; match to protein family HMM PF01050; match to protein family HMM PF07883; match to protein family HMM TIGR01479; Belongs to the mannose-6-phosphate isomerase type 2 family.
  
  
 0.854
AFE_0074
Chain length determinant family protein; Identified by match to protein family HMM PF02706.
  
  
 0.712
AFE_1357
Glycosyl transferase, group 1; Identified by match to protein family HMM PF00534.
 
    0.663
AFE_1339
Polysaccharide biosynthesis/export domain protein; Identified by match to protein family HMM PF02563.
 
  
 0.624
mtfA
Mannosyltransferase; Identified by similarity to GB:AAF04384.1; match to protein family HMM PF00534.
 
    0.588
AFE_1346
Glycosyl transferase, group 2 family protein; Identified by match to protein family HMM PF00535.
 
  
 0.580
gmd-1
GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.
  
  
 0.572
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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