Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_0075Conserved hypothetical protein; Identified by similarity to GB:AAN48775.1; match to protein family HMM PF01047. (119 aa)    
Predicted Functional Partners:
AFE_0074
Chain length determinant family protein; Identified by match to protein family HMM PF02706.
 
     0.736
AFE_0076
Polysaccharide biosynthesis protein; Identified by similarity to SP:P37781; match to protein family HMM PF01943.
  
    0.461
AFE_3010
Polyketide synthase, type I, putative; Identified by similarity to GB:AAK26474.1; match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM PF08240; match to protein family HMM PF08659.
  
  
 0.458
AFE_0077
Conserved hypothetical protein; Identified by similarity to GB:AAN49860.1; match to protein family HMM PF08241; match to protein family HMM PF08242.
       0.448
AFE_0073
Undecaprenyl-phosphate galactosephosphotransferase; Identified by similarity to SP:P26406; match to protein family HMM PF02397; match to protein family HMM TIGR03022; match to protein family HMM TIGR03025.
     
 0.440
AFE_2148
DNA-binding protein, putative; Identified by similarity to GB:AAO56394.1; match to protein family HMM PF01381; match to protein family HMM PF07883.
  
 
 0.418
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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