AFE_0105 protein (Acidithiobacillus ferrooxidans)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

AFE_0105

Metal ion transporter, NRAMP family; Identified by match to protein family HMM PF01566. (421 aa)

Predicted Functional Partners:

AFE_2018

0.678

AFE_1498

0.623

AFE_2307

0.582

AFE_0106

0.577

AFE_2019

0.577

AFE_3090

0.555

AFE_0107

0.547

AFE_2330

0.547

AFE_1716

0.524

AFE_0439

0.512

Your Current Organism:

Acidithiobacillus ferrooxidans

NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
AFE_0105	AFE_0106	Metal ion transporter, NRAMP family; Identified by match to protein family HMM PF01566.	Sensor histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518.	0.577
AFE_0105	AFE_0107	Metal ion transporter, NRAMP family; Identified by match to protein family HMM PF01566.	DNA-binding response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486.	0.547
AFE_0105	AFE_0439	Metal ion transporter, NRAMP family; Identified by match to protein family HMM PF01566.	Amino acid permease family protein; Identified by match to protein family HMM PF00324.	0.512
AFE_0105	AFE_1498	Metal ion transporter, NRAMP family; Identified by match to protein family HMM PF01566.	ABC transporter, periplasmic substrate-binding protein, putative; Identified by match to protein family HMM PF01547.	0.623
AFE_0105	AFE_1716	Metal ion transporter, NRAMP family; Identified by match to protein family HMM PF01566.	GTP-binding protein.	0.524
AFE_0105	AFE_2018	Metal ion transporter, NRAMP family; Identified by match to protein family HMM PF01566.	Conserved hypothetical protein; Identified by similarity to PIR:C70988.	0.678
AFE_0105	AFE_2019	Metal ion transporter, NRAMP family; Identified by match to protein family HMM PF01566.	Conserved domain protein.	0.577
AFE_0105	AFE_2307	Metal ion transporter, NRAMP family; Identified by match to protein family HMM PF01566.	Conserved domain protein; Identified by similarity to GB:AAO90256.1.	0.582
AFE_0105	AFE_2330	Metal ion transporter, NRAMP family; Identified by match to protein family HMM PF01566.	Membrane protein, putative; Identified by match to protein family HMM PF03988.	0.547
AFE_0105	AFE_3090	Metal ion transporter, NRAMP family; Identified by match to protein family HMM PF01566.	Membrane protein, putative; Identified by match to protein family HMM PF07690.	0.555
AFE_0106	AFE_0105	Sensor histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518.	Metal ion transporter, NRAMP family; Identified by match to protein family HMM PF01566.	0.577
AFE_0106	AFE_0107	Sensor histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518.	DNA-binding response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486.	0.996
AFE_0107	AFE_0105	DNA-binding response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486.	Metal ion transporter, NRAMP family; Identified by match to protein family HMM PF01566.	0.547
AFE_0107	AFE_0106	DNA-binding response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486.	Sensor histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518.	0.996
AFE_0439	AFE_0105	Amino acid permease family protein; Identified by match to protein family HMM PF00324.	Metal ion transporter, NRAMP family; Identified by match to protein family HMM PF01566.	0.512
AFE_0439	AFE_1498	Amino acid permease family protein; Identified by match to protein family HMM PF00324.	ABC transporter, periplasmic substrate-binding protein, putative; Identified by match to protein family HMM PF01547.	0.514
AFE_0439	AFE_2330	Amino acid permease family protein; Identified by match to protein family HMM PF00324.	Membrane protein, putative; Identified by match to protein family HMM PF03988.	0.463
AFE_1498	AFE_0105	ABC transporter, periplasmic substrate-binding protein, putative; Identified by match to protein family HMM PF01547.	Metal ion transporter, NRAMP family; Identified by match to protein family HMM PF01566.	0.623
AFE_1498	AFE_0439	ABC transporter, periplasmic substrate-binding protein, putative; Identified by match to protein family HMM PF01547.	Amino acid permease family protein; Identified by match to protein family HMM PF00324.	0.514
AFE_1498	AFE_1716	ABC transporter, periplasmic substrate-binding protein, putative; Identified by match to protein family HMM PF01547.	GTP-binding protein.	0.627