Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-expression
Experiments
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[Homology]
Score
AFE_0124TPR domain protein; Identified by match to protein family HMM PF00515. (175 aa)    
Predicted Functional Partners:
AFE_0122
Conserved domain protein.
       0.781
gcp
O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
       0.781
AFE_2385
SCP-2 sterol transfer family protein; Identified by match to protein family HMM PF02036.
 
     0.707
AFE_2896
Identified by match to protein family HMM PF04932.
 
     0.670
AFE_2533
Oxidoreductase, aldo/keto reductase family; Identified by match to protein family HMM PF00248.
  
     0.615
AFE_2325
Hypothetical protein; Identified by glimmer; putative.
  
     0.570
AFE_0121
Hypothetical protein; Identified by glimmer; putative.
       0.549
AFE_0721
Conserved hypothetical protein; Identified by similarity to PIR:A97389.
  
     0.520
AFE_0169
Conserved domain protein; Identified by similarity to GB:CAD74705.1.
  
     0.499
AFE_1338
Identified by match to protein family HMM PF01569.
 
     0.493
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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