Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_0139Conserved hypothetical protein; Identified by similarity to PIR:A81668. (254 aa)    
Predicted Functional Partners:
AFE_0140
Oxidase, FAD-binding; Identified by match to protein family HMM PF01565; match to protein family HMM PF02913.
       0.805
AFE_0142
Conserved hypothetical protein TIGR00252; Identified by match to protein family HMM PF02021; match to protein family HMM TIGR00252; Belongs to the UPF0102 family.
       0.805
AFE_0143
Lipoprotein, putative.
       0.805
gmhA-2
Phosphoheptose isomerase/cytidylyltransferase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. Belongs to the SIS family. GmhA subfamily.
       0.778
AFE_0138
LPS heptosyltransferase II; Identified by similarity to GB:AAL23754.1; match to protein family HMM PF01075; match to protein family HMM TIGR02195.
       0.724
AFE_1964
Fatty acid desaturase; Identified by match to protein family HMM PF00487.
  
     0.692
AFE_2896
Identified by match to protein family HMM PF04932.
  
     0.642
AFE_0169
Conserved domain protein; Identified by similarity to GB:CAD74705.1.
  
     0.630
AFE_2037
Outer membrane efflux protein; Identified by match to protein family HMM PF02321.
  
     0.578
rsmI
Tetrapyrrole methylase family protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
       0.576
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.