Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_0140Oxidase, FAD-binding; Identified by match to protein family HMM PF01565; match to protein family HMM PF02913. (461 aa)    
Predicted Functional Partners:
AFE_0139
Conserved hypothetical protein; Identified by similarity to PIR:A81668.
       0.805
AFE_0142
Conserved hypothetical protein TIGR00252; Identified by match to protein family HMM PF02021; match to protein family HMM TIGR00252; Belongs to the UPF0102 family.
       0.805
AFE_0143
Lipoprotein, putative.
       0.805
gmhA-2
Phosphoheptose isomerase/cytidylyltransferase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. Belongs to the SIS family. GmhA subfamily.
       0.800
AFE_0138
LPS heptosyltransferase II; Identified by similarity to GB:AAL23754.1; match to protein family HMM PF01075; match to protein family HMM TIGR02195.
       0.724
glcF
Glycolate oxidase, iron-sulfur subunit; Identified by similarity to SP:P52074; match to protein family HMM PF00037; match to protein family HMM PF02754.
 
  
 0.639
fixB
Electron transfer flavoprotein, alpha subunit; Identified by similarity to SP:P26483; match to protein family HMM PF00766; match to protein family HMM PF01012.
 
 
 0.618
fixA
Electron transfer flavoprotein, beta subunit; Identified by similarity to SP:P53577; match to protein family HMM PF01012.
 
 
 0.588
rsmI
Tetrapyrrole methylase family protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
       0.576
AFE_3010
Polyketide synthase, type I, putative; Identified by similarity to GB:AAK26474.1; match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM PF08240; match to protein family HMM PF08659.
  
 
 0.517
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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