Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AFE_0143Lipoprotein, putative. (612 aa)    
Predicted Functional Partners:
AFE_0142
Conserved hypothetical protein TIGR00252; Identified by match to protein family HMM PF02021; match to protein family HMM TIGR00252; Belongs to the UPF0102 family.
 
  
 0.846
gmhA-2
Phosphoheptose isomerase/cytidylyltransferase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. Belongs to the SIS family. GmhA subfamily.
  
    0.831
AFE_0139
Conserved hypothetical protein; Identified by similarity to PIR:A81668.
       0.805
AFE_0140
Oxidase, FAD-binding; Identified by match to protein family HMM PF01565; match to protein family HMM PF02913.
       0.805
AFE_0138
LPS heptosyltransferase II; Identified by similarity to GB:AAL23754.1; match to protein family HMM PF01075; match to protein family HMM TIGR02195.
 
     0.755
AFE_2223
Penicillin-binding protein 1A, putative; Identified by similarity to SP:P31776; match to protein family HMM PF00905; match to protein family HMM PF00912.
    
 
 0.706
AFE_1915
Type IV pilus assembly protein PilZ, putative; Identified by similarity to PIR:B59241; match to protein family HMM PF07238.
  
     0.610
rsmI
Tetrapyrrole methylase family protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
       0.608
AFE_0736
Type 4 fimbrial biogenesis protein PilP, putative; Identified by similarity to GB:AAA93089.1.
  
     0.473
ftsL
Cell division protein FtsL; Essential cell division protein; Belongs to the FtsL family.
  
     0.442
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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