STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFE_0150Conserved hypothetical protein; Identified by similarity to GB:CAE33855.1. (264 aa)    
Predicted Functional Partners:
speH
S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
 
 
 0.990
speE
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
  
  
  0.928
AFE_2526
Hydrolase, carbon-nitrogen family; Identified by match to protein family HMM PF00795; match to protein family HMM TIGR03381.
  
 
 0.910
AFE_1826
Identified by match to protein family HMM PF01979; match to protein family HMM PF07969.
   
  0.908
AFE_2160
Conserved hypothetical protein; Identified by similarity to GB:CAE33855.1.
  
  
 
0.902
AFE_1999
Autoinducer synthesis protein; Identified by similarity to SP:P12747; match to protein family HMM PF00765.
     
  0.900
AFE_2123
MTA/SAH nucleosidase, putative; Identified by similarity to SP:P24247; match to protein family HMM PF01048; match to protein family HMM TIGR03468.
     
  0.900
AFE_0148
Hypothetical protein; Identified by glimmer; putative.
       0.661
AFE_0151
Rhodanese-like domain protein; Identified by match to protein family HMM PF00581.
  
    0.511
AFE_0152
Conserved hypothetical protein; Identified by similarity to PIR:D84128; match to protein family HMM PF04241.
       0.454
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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