Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AFE_0163ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. (306 aa)    
Predicted Functional Partners:
AFE_2864
ABC transporter, permease protein, putative; Identified by similarity to SP:P75774; match to protein family HMM PF01061.
 
    0.903
AFE_3036
ABC-2 type transporter; Identified by match to protein family HMM PF01061.
  
 0.872
AFE_1604
ABC transporter, permease protein, putative; Identified by similarity to SP:P75775; match to protein family HMM PF01061.
 
    0.842
AFE_1603
ABC transporter, permease protein, putative; Identified by similarity to SP:P75774; match to protein family HMM PF01061.
 
    0.839
AFE_2863
ABC transporter, permease protein, putative; Identified by similarity to SP:P75775; match to protein family HMM PF01061.
 
    0.833
AFE_0162
Conserved hypothetical protein; Identified by similarity to GB:CAD16664.1.
       0.805
AFE_0164
S4 domain protein; Identified by match to protein family HMM PF01479.
       0.783
pdxA
4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
       0.783
AFE_0161
Toluene tolerance protein, putative; Identified by match to protein family HMM PF05494.
  
    0.594
AFE_0158
Toluene ABC transporter, ATP-binding protein, putative; Identified by similarity to GB:AAD17957.1; match to protein family HMM PF00005.
 
    
0.580
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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