Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AFE_0169Conserved domain protein; Identified by similarity to GB:CAD74705.1. (155 aa)    
Predicted Functional Partners:
ksgA
Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
       0.805
AFE_2325
Hypothetical protein; Identified by glimmer; putative.
  
     0.765
AFE_2896
Identified by match to protein family HMM PF04932.
  
     0.761
AFE_1964
Fatty acid desaturase; Identified by match to protein family HMM PF00487.
  
     0.661
AFE_2385
SCP-2 sterol transfer family protein; Identified by match to protein family HMM PF02036.
  
    0.654
AFE_0577
Membrane protein, putative; Identified by match to protein family HMM PF03706; match to protein family HMM TIGR00374.
  
     0.645
AFE_0458
Rare lipoprotein B, putative; Identified by similarity to SP:P10101.
  
     0.636
AFE_0139
Conserved hypothetical protein; Identified by similarity to PIR:A81668.
  
     0.630
AFE_0168
Hypothetical protein; Identified by glimmer; putative.
  
     0.623
AFE_2575
Conserved domain protein; Identified by similarity to GB:AAD20272.1.
  
     0.617
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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