Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
rlmJConserved hypothetical protein; Specifically methylates the adenine in position 2030 of 23S rRNA. (285 aa)    
Predicted Functional Partners:
prmB
Ribosomal protein L3 N-methyltransferase; Identified by match to protein family HMM PF05175; match to protein family HMM PF08242; match to protein family HMM TIGR00536; match to protein family HMM TIGR03533; Belongs to the protein N5-glutamine methyltransferase family.
 
    0.805
AFE_0175
Hypothetical protein; Identified by glimmer; putative.
       0.785
xth-2
Exodeoxyribonuclease III; Identified by match to protein family HMM PF03372; match to protein family HMM TIGR00195; match to protein family HMM TIGR00633.
       0.769
AFE_0177
Identified by similarity to GB:AAQ60970.1; match to protein family HMM PF02798.
 
     0.650
xth-1
Exodeoxyribonuclease III; Identified by match to protein family HMM PF03372; match to protein family HMM TIGR00195; match to protein family HMM TIGR00633.
       0.548
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
       0.548
aroE
Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
 
     0.444
AFE_0180
Peptidyl-prolyl cis-trans isomerase, FKBP-type; Identified by similarity to SP:P30856; match to protein family HMM PF00254.
       0.433
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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