Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_0199Conserved hypothetical protein; Identified by similarity to GB:CAE34827.1. (285 aa)    
Predicted Functional Partners:
AFE_3120
Membrane protein, putative.
  
     0.628
AFE_2707
Conserved hypothetical protein; Identified by similarity to GB:CAE42273.1; match to protein family HMM PF07811.
  
     0.622
resB
Cytochrome c-type biogenesis protein ResB; Identified by match to protein family HMM PF05140.
  
     0.598
resC
Cytochrome c-type biogenesis protein ResC; Identified by match to protein family HMM PF01578; match to protein family HMM TIGR03144.
  
     0.545
AFE_1769
Oxidoreductase, FAD-binding, putative; Identified by similarity to GB:AAQ61895.1; match to protein family HMM PF01565; match to protein family HMM PF02754; match to protein family HMM PF02913.
  
     0.462
AFE_2699
Lipoprotein, putative; Identified by match to protein family HMM PF00515; match to protein family HMM PF07719.
  
     0.457
AFE_2494
Conserved hypothetical protein; Identified by similarity to GB:AAQ59662.1.
  
     0.456
AFE_0444
Conserved hypothetical protein; Identified by similarity to GB:AAQ59662.1.
  
     0.453
AFE_3127
Conserved hypothetical protein; Identified by similarity to GB:CAD16125.1; match to protein family HMM PF01903.
  
   
 0.453
AFE_2697
Conserved hypothetical protein; Identified by similarity to PIR:H83107.
  
     0.414
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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