Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Experiments
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[Homology]
Score
AFE_0230Glycosyl transferase, group 1 family protein; Identified by match to protein family HMM PF00534. (336 aa)    
Predicted Functional Partners:
AFE_0229
Identified by match to protein family HMM PF01522.
 
    0.680
AFE_1349
Glycosyl transferase, group 1 family protein; Identified by match to protein family HMM PF00534.
  
     0.633
AFE_0227
Mutator mutT protein/thiamine-phosphate pyrophosphorylase family protein; Identified by match to protein family HMM PF00293; match to protein family HMM PF02581; match to protein family HMM TIGR00586; Belongs to the Nudix hydrolase family.
  
  
 0.618
AFE_0228
Glycosyl transferase, group 2 family protein; Identified by match to protein family HMM PF00535.
  
    0.610
secA
Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family.
   
 
 0.591
argJ
Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
       0.580
AFE_0224
Hypothetical protein; Identified by glimmer; putative.
       0.543
AFE_0616
Glycosyltransferase, group 1; Identified by match to protein family HMM PF00534.
  
     0.524
AFE_1354
Glycosyl transferase, group 1 family protein; Identified by match to protein family HMM PF00534.
  
     0.513
AFE_0234
Lipopolysaccharide core biosynthesis glycosyl transferase; Identified by similarity to SP:Q9XC90; match to protein family HMM PF00535.
 
    0.438
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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