Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AFE_0231Identified by match to protein family HMM PF02366. (463 aa)    
Predicted Functional Partners:
AFE_0234
Lipopolysaccharide core biosynthesis glycosyl transferase; Identified by similarity to SP:Q9XC90; match to protein family HMM PF00535.
 
  
 0.662
AFE_0232
Identified by match to protein family HMM PF04932.
       0.621
AFE_0228
Glycosyl transferase, group 2 family protein; Identified by match to protein family HMM PF00535.
 
  
 0.508
AFE_0233
Glycosyl transferase, group 2 family protein; Identified by match to protein family HMM PF00535.
     
 0.507
rfaC
Lipopolysaccharide heptosyltransferase 1; Identified by similarity to SP:P24173; match to protein family HMM PF01075; match to protein family HMM TIGR02193.
       0.506
AFE_0236
Conserved hypothetical protein; Identified by similarity to GB:AAK22293.1.
       0.502
kdtA
3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
       0.502
AFE_0229
Identified by match to protein family HMM PF01522.
  
    0.468
AFE_0230
Glycosyl transferase, group 1 family protein; Identified by match to protein family HMM PF00534.
       0.420
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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