Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AFE_0240Conserved hypothetical protein; Identified by similarity to GB:CAD86313.1; match to protein family HMM PF03781; match to protein family HMM PF08241; match to protein family HMM PF08242. (702 aa)    
Predicted Functional Partners:
AFE_0239
Aminotransferase, class II; Identified by similarity to SP:P23256; similarity to SP:Q08432; match to protein family HMM PF00155.
 
     0.842
AFE_3222
Identified by match to protein family HMM PF03747.
 
     0.703
comF
Competence protein; Identified by similarity to SP:P31773.
  
    0.659
trmL
RNA methyltransferase, TrmH family, group 2; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.
       0.654
AFE_0654
ABC transporter, permease protein; Identified by match to protein family HMM PF02687.
 
  
 0.593
bioF
8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
  
  
 0.553
AFE_0238
Lipid A biosynthesis lauroyl acyltransferase; Identified by similarity to SP:P24187; match to protein family HMM PF03279.
       0.529
bioD-2
Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
  
  
 0.526
bioH
bioH protein; Identified by similarity to SP:P13001; match to protein family HMM PF00561; match to protein family HMM TIGR01738.
     
 0.502
AFE_3010
Polyketide synthase, type I, putative; Identified by similarity to GB:AAK26474.1; match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM PF08240; match to protein family HMM PF08659.
  
 
 0.486
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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