Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pilT-2Twitching motility protein PilT; Identified by similarity to SP:P24559; match to protein family HMM PF00437; match to protein family HMM TIGR01420. (349 aa)    
Predicted Functional Partners:
pilC
Type IV pilus biogenesis protein PilC; Identified by similarity to SP:P45793; match to protein family HMM PF00482.
 
  
 0.864
pilD
Type IV pilus prepilin peptidase PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
 
   
 0.859
AFE_0739
Type IV pilus assembly protein PilM; Identified by similarity to PIR:S77726; match to protein family HMM TIGR01175.
 
   
 0.839
pilT-1
Twitching motility protein PilT; Identified by similarity to GB:AAL37755.1; match to protein family HMM PF00437; match to protein family HMM TIGR01420.
 
  
0.838
AFE_0266
Glycosyl transferase, group 2 family protein; Identified by match to protein family HMM PF00535; match to protein family HMM TIGR03469.
     
 0.801
AFE_0735
Fimbrial assembly protein PilQ, putative; Identified by similarity to SP:P34750; match to protein family HMM PF00263; match to protein family HMM PF03958; match to protein family HMM PF07660; match to protein family HMM TIGR02515.
 
   
 0.782
AFE_0737
Fimbrial assembly protein PilO, putative; Identified by match to protein family HMM PF04350.
 
  
 0.686
AFE_0738
Type IV pilus biogenesis protein PilN; Identified by match to protein family HMM PF05137.
 
  
 0.623
AFE_0261
Identified by match to protein family HMM PF02325.
       0.598
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
       0.598
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.