Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AFE_0268Conserved domain protein; Identified by similarity to GB:CAD79002.1. (205 aa)    
Predicted Functional Partners:
AFE_0269
Identified by similarity to PIR:S74892; match to protein family HMM PF00753.
       0.762
AFE_1547
Membrane protein, putative; Identified by match to protein family HMM PF07690.
  
     0.627
AFE_2019
Conserved domain protein.
  
     0.620
sqr
Sulfide quinone reductase, putative; Identified by similarity to GB:AAF72963.1; match to protein family HMM PF07992.
 
     0.570
AFE_1218
Conserved domain protein; Identified by similarity to PIR:A97990.
  
     0.491
AFE_0270
Transcriptional regulator, Crp/Fnr family; Identified by match to protein family HMM PF00027; match to protein family HMM PF00325.
       0.476
trmB
tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
       0.476
AFE_2368
Outer membrane efflux protein; Identified by match to protein family HMM PF02321.
  
     0.420
AFE_0966
Conserved hypothetical protein.
  
     0.419
AFE_0967
Type IV pilin biogenesis protein, putative; Identified by similarity to GB:AAQ58159.1.
  
     0.415
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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