Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_0286Identified by match to protein family HMM PF00916. (516 aa)    
Predicted Functional Partners:
AFE_0287
Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.
  
 0.987
AFE_3010
Polyketide synthase, type I, putative; Identified by similarity to GB:AAK26474.1; match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM PF08240; match to protein family HMM PF08659.
 
 
 0.913
AFE_1502
Ankyrin repeat protein/rhodanese-like domain protein; Identified by match to protein family HMM PF00023; match to protein family HMM PF00581.
   
 
 0.824
AFE_0236
Conserved hypothetical protein; Identified by similarity to GB:AAK22293.1.
   
   0.803
AFE_1227
Identified by match to protein family HMM PF00149.
   
   0.791
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
    
 
 0.782
AFE_3118
Pyridine nucleotide-disulfide oxidoreductase; Identified by similarity to SP:Q9R112; match to protein family HMM PF07992.
  
  
 0.742
nuoM
NADH-quinone oxidoreductase, M subunit; Identified by similarity to SP:P50974; match to protein family HMM PF00361; match to protein family HMM TIGR01972.
  
 
 0.679
petB-2
Ubiquinol--cytochrome c reductase, cytochrome b subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
    
   0.654
petB-1
Ubiquinol--cytochrome c reductase, cytochrome b subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
    
   0.654
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
Server load: low (18%) [HD]