Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AFE_0306OmpA family protein; Identified by similarity to SP:Q05146; match to protein family HMM PF00691. (217 aa)    
Predicted Functional Partners:
AFE_1453
Outer membrane protein, OmpH family; Identified by match to protein family HMM PF03938.
 
 
 0.668
tolB
Tol-pal system beta propeller repeat protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
 
 
 0.620
AFE_0307
Hypothetical protein; Identified by glimmer; putative.
       0.572
ubiB
2-polyprenylphenol 6-hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. Belongs to the ABC1 family. UbiB subfamily.
       0.540
AFE_0531
Conserved domain protein; Identified by similarity to GB:AAK57731.1.
 
      0.532
lolC
Lipoprotein releasing system transmembrane protein LolC; Identified by similarity to SP:P75956; match to protein family HMM PF02687; match to protein family HMM TIGR02212.
  
 
   0.527
AFE_0304
Conserved hypothetical protein; Identified by similarity to GB:AAM24168.1.
 
     0.497
bamA
Outer membrane protein, OMP85 family; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
 
 0.469
AFE_2763
Outer membrane lipoprotein LolB, putative; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
   
 
 0.462
tetH
Tetrathionate hydrolase; Catalyzes the hydrolysis of tetrathionate to generate elemental sulfur, thiosulfate and sulfate.
   
  
 0.459
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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