STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gorGlutathione reductase; Identified by similarity to SP:P06715; match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01421. (449 aa)    
Predicted Functional Partners:
AFE_0367
AhpC/TSA family/glutaredoxin domain protein; Identified by match to protein family HMM PF00462; match to protein family HMM PF00578; match to protein family HMM PF08534; match to protein family HMM TIGR02190.
 
 0.983
gshB
Glutathione synthetase; Identified by similarity to SP:P04425; match to protein family HMM PF02951; match to protein family HMM PF02955; match to protein family HMM PF08443; match to protein family HMM TIGR01380; Belongs to the prokaryotic GSH synthase family.
     
 0.946
AFE_2848
Thioredoxin, putative; Identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068.
   
 
 0.921
AFE_0177
Identified by similarity to GB:AAQ60970.1; match to protein family HMM PF02798.
   
 0.918
AFE_1474
Glutathione S-transferase, putative; Identified by similarity to SP:P39100; match to protein family HMM PF02798.
   
 0.916
gst
Glutathione S-transferase; Identified by similarity to GB:CAB57289.1; match to protein family HMM PF00043; match to protein family HMM PF02798.
   
 0.916
AFE_0291
Identified by match to protein family HMM PF02798.
   
 0.913
AFE_1811
2-oxo acid dehydrogenase, acyltransferase, putative; Identified by match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817.
 
 0.826
pdhC
Pyruvate dehydrogenase complex, E2 and E3 components; Dihydrolipoamide acetyltransferase/dihydrolipoamide dehydrogenase; identified by similarity to PIR:C59237; match to protein family HMM PF00070; match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817; match to protein family HMM PF02852; match to protein family HMM PF07992.
 
0.799
AFE_1812
Dehydrogenase complex, E1 component, beta subunit, putative; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 
 0.737
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
Server load: medium (54%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.