STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFE_0401roadblock/LC7 domain protein; Identified by match to protein family HMM PF03259. (136 aa)    
Predicted Functional Partners:
AFE_2576
Small GTP-binding protein; Identified by match to protein family HMM PF03029; match to protein family HMM TIGR00231.
 
 
 0.962
AFE_2575
Conserved domain protein; Identified by similarity to GB:AAD20272.1.
 
 
 0.960
AFE_2577
Conserved hypothetical protein; Identified by similarity to PIR:A81195.
 
    0.791
AFE_2384
Conserved hypothetical protein; Identified by similarity to PIR:A82245.
 
     0.775
gloA
Lactoylglutathione lyase; Identified by match to protein family HMM PF00903; match to protein family HMM TIGR00068.
       0.539
AFE_0403
Conserved hypothetical protein; Identified by similarity to GB:AAN48171.1.
       0.535
argG
Argininosuccinate synthase; Identified by similarity to SP:Q9HY84; match to protein family HMM PF00764; match to protein family HMM TIGR00032; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
       0.535
argF
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
       0.535
argD
Acetylornithine aminotransferase; Identified by similarity to SP:P54752; match to protein family HMM PF00202; match to protein family HMM TIGR00707; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
       0.535
AFE_0407
Aspartate kinase, monofunctional class; Identified by similarity to SP:P41403; match to protein family HMM PF00696; match to protein family HMM PF01842; match to protein family HMM TIGR00656; match to protein family HMM TIGR00657; Belongs to the aspartokinase family.
       0.535
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.