Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AFE_0410Hypothetical protein; Identified by glimmer; putative. (52 aa)    
Predicted Functional Partners:
AFE_0409
Conserved domain protein; Identified by similarity to GB:AAN79743.1; match to protein family HMM PF08238.
       0.773
AFE_0411
Hypothetical protein; Identified by glimmer; putative.
       0.773
AFE_0412
Addiction module toxin, Txe/YoeB family; Identified by match to protein family HMM PF06769; match to protein family HMM TIGR02116.
       0.661
AFE_0408
Hypothetical protein; Identified by glimmer; putative.
       0.634
AFE_0413
PIN domain protein; Identified by match to protein family HMM PF01850.
       0.508
AFE_0414
Prevent host death protein; Antitoxin component of a type II toxin-antitoxin (TA) system.
       0.508
AFE_0403
Conserved hypothetical protein; Identified by similarity to GB:AAN48171.1.
       0.434
argG
Argininosuccinate synthase; Identified by similarity to SP:Q9HY84; match to protein family HMM PF00764; match to protein family HMM TIGR00032; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
       0.434
argF
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
       0.434
argD
Acetylornithine aminotransferase; Identified by similarity to SP:P54752; match to protein family HMM PF00202; match to protein family HMM TIGR00707; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
       0.434
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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