Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_0416Pilin, putative; Identified by match to protein family HMM PF07963; match to protein family HMM TIGR02532. (178 aa)    
Predicted Functional Partners:
pilC
Type IV pilus biogenesis protein PilC; Identified by similarity to SP:P45793; match to protein family HMM PF00482.
 
  
 0.904
AFE_0970
Type IV pilin, putative; Identified by similarity to GB:AAB48595.1; match to protein family HMM PF07963; match to protein family HMM TIGR02532.
  
 
 0.852
AFE_0183
Type IV pilus assembly protein; Identified by similarity to SP:P45792; match to protein family HMM PF00437; match to protein family HMM PF05157; match to protein family HMM TIGR02538.
 
 
 0.843
AFE_1087
Type II/IV secretion system protein; Identified by match to protein family HMM PF00437.
  
 
 0.806
AFE_0735
Fimbrial assembly protein PilQ, putative; Identified by similarity to SP:P34750; match to protein family HMM PF00263; match to protein family HMM PF03958; match to protein family HMM PF07660; match to protein family HMM TIGR02515.
 
   
 0.778
AFE_0738
Type IV pilus biogenesis protein PilN; Identified by match to protein family HMM PF05137.
 
  
 0.774
AFE_0737
Fimbrial assembly protein PilO, putative; Identified by match to protein family HMM PF04350.
 
  
 0.773
AFE_0739
Type IV pilus assembly protein PilM; Identified by similarity to PIR:S77726; match to protein family HMM TIGR01175.
 
  
 0.712
AFE_0018
LysM domain protein; Identified by match to protein family HMM PF01476.
  
     0.685
pilD
Type IV pilus prepilin peptidase PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
 
  
 0.615
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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