Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_0439Amino acid permease family protein; Identified by match to protein family HMM PF00324. (528 aa)    
Predicted Functional Partners:
AFE_0440
Hypothetical protein; Identified by glimmer; putative.
       0.773
AFE_1809
Identified by similarity to SP:Q46909; match to protein family HMM PF00083; match to protein family HMM PF07690.
  
     0.646
rfbB
dTDP-glucose 4,6-dehydratase; Identified by similarity to SP:P55295; match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01181; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
       0.590
AFE_2277
Major facilitator family transporter; Identified by match to protein family HMM PF00083; match to protein family HMM PF07690.
  
     0.579
AFE_2659
Amino acid permease family protein; Identified by match to protein family HMM PF00324.
  
     0.578
AFE_3296
Major facilitator family transporter; Identified by match to protein family HMM PF00083; match to protein family HMM PF07690.
  
     0.571
rfbD
dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family.
       0.554
AFE_0719
Amino acid permease family protein; Identified by match to protein family HMM PF00324.
  
     0.551
AFE_1498
ABC transporter, periplasmic substrate-binding protein, putative; Identified by match to protein family HMM PF01547.
  
     0.514
AFE_0105
Metal ion transporter, NRAMP family; Identified by match to protein family HMM PF01566.
 
     0.512
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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