node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AFE_0447 | AFE_0448 | AFE_0447 | AFE_0448 | Sigma-54 dependent DNA-binding response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00158; match to protein family HMM PF07728. | Lipoprotein, putative. | 0.808 |
AFE_0447 | AFE_0449 | AFE_0447 | AFE_0449 | Sigma-54 dependent DNA-binding response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00158; match to protein family HMM PF07728. | Sensor histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518. | 0.985 |
AFE_0447 | ppnK | AFE_0447 | AFE_0451 | Sigma-54 dependent DNA-binding response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00158; match to protein family HMM PF07728. | ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.468 |
AFE_0447 | recN | AFE_0447 | AFE_0450 | Sigma-54 dependent DNA-binding response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00158; match to protein family HMM PF07728. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.468 |
AFE_0448 | AFE_0447 | AFE_0448 | AFE_0447 | Lipoprotein, putative. | Sigma-54 dependent DNA-binding response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00158; match to protein family HMM PF07728. | 0.808 |
AFE_0448 | AFE_0449 | AFE_0448 | AFE_0449 | Lipoprotein, putative. | Sensor histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518. | 0.808 |
AFE_0448 | ppnK | AFE_0448 | AFE_0451 | Lipoprotein, putative. | ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.468 |
AFE_0448 | recN | AFE_0448 | AFE_0450 | Lipoprotein, putative. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.468 |
AFE_0449 | AFE_0447 | AFE_0449 | AFE_0447 | Sensor histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518. | Sigma-54 dependent DNA-binding response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00158; match to protein family HMM PF07728. | 0.985 |
AFE_0449 | AFE_0448 | AFE_0449 | AFE_0448 | Sensor histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518. | Lipoprotein, putative. | 0.808 |
AFE_0449 | ppnK | AFE_0449 | AFE_0451 | Sensor histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518. | ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.468 |
AFE_0449 | recN | AFE_0449 | AFE_0450 | Sensor histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.468 |
birA | coaX | AFE_0453 | AFE_0452 | birA bifunctional protein; Identified by match to protein family HMM PF02237; match to protein family HMM PF03099; match to protein family HMM TIGR00121. | Transcriptional activator, putative, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.863 |
birA | nadE | AFE_0453 | AFE_0428 | birA bifunctional protein; Identified by match to protein family HMM PF02237; match to protein family HMM PF03099; match to protein family HMM TIGR00121. | Glutamine-dependent NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.455 |
birA | ppnK | AFE_0453 | AFE_0451 | birA bifunctional protein; Identified by match to protein family HMM PF02237; match to protein family HMM PF03099; match to protein family HMM TIGR00121. | ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.558 |
birA | proA | AFE_0453 | AFE_0454 | birA bifunctional protein; Identified by match to protein family HMM PF02237; match to protein family HMM PF03099; match to protein family HMM TIGR00121. | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.746 |
birA | recN | AFE_0453 | AFE_0450 | birA bifunctional protein; Identified by match to protein family HMM PF02237; match to protein family HMM PF03099; match to protein family HMM TIGR00121. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.560 |
coaX | birA | AFE_0452 | AFE_0453 | Transcriptional activator, putative, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | birA bifunctional protein; Identified by match to protein family HMM PF02237; match to protein family HMM PF03099; match to protein family HMM TIGR00121. | 0.863 |
coaX | ppnK | AFE_0452 | AFE_0451 | Transcriptional activator, putative, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.570 |
coaX | proA | AFE_0452 | AFE_0454 | Transcriptional activator, putative, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.738 |