Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
wrbATrp repressor binding protein; Identified by similarity to SP:P30849; match to protein family HMM PF00258; match to protein family HMM TIGR01755. (200 aa)    
Predicted Functional Partners:
AFE_3223
WrbA family protein; Identified by similarity to SP:P30849; Belongs to the WrbA family.
  
  
 
0.902
ubiE
Ubiquinone/menaquinone biosynthesis methlytransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).
     
  0.900
AFE_0115
Conserved domain protein; Identified by match to protein family HMM PF03724.
   
    0.753
AFE_0461
Identified by match to protein family HMM PF04264; Belongs to the UPF0312 family.
       0.740
AFE_1802
Fructose-bisphosphate aldolase, putative; Identified by similarity to SP:P58315; match to protein family HMM PF01791.
   
    0.683
ddpX
D-alanyl-d-alanine dipeptidase, putative; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.
       0.539
rho
Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.
      
 0.506
groES
Chaperonin, 10 kDa; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
      
 0.504
AFE_0018
LysM domain protein; Identified by match to protein family HMM PF01476.
   
  
 0.496
AFE_2910
Conserved hypothetical protein; Identified by match to protein family HMM PF06798; match to protein family HMM PF08298.
   
    0.470
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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