Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AFE_0464Hypothetical protein; Identified by glimmer; putative. (170 aa)    
Predicted Functional Partners:
AFE_0463
formamidopyrimidine-DNA glycosylase, putative; Identified by match to protein family HMM PF06831; Belongs to the FPG family.
       0.768
ddpX
D-alanyl-d-alanine dipeptidase, putative; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.
       0.613
AFE_0465
Identified by match to protein family HMM PF01545; match to protein family HMM TIGR01297; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
       0.472
AFE_0461
Identified by match to protein family HMM PF04264; Belongs to the UPF0312 family.
       0.461
wrbA
Trp repressor binding protein; Identified by similarity to SP:P30849; match to protein family HMM PF00258; match to protein family HMM TIGR01755.
       0.437
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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