Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_0475Conserved hypothetical protein; Identified by similarity to GB:AAQ60147.1. (321 aa)    
Predicted Functional Partners:
thrC
Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
       0.805
recJ
single-stranded-DNA-specific exonuclease RecJ; Identified by similarity to SP:P21893; match to protein family HMM PF01368.
       0.799
AFE_0168
Hypothetical protein; Identified by glimmer; putative.
  
     0.758
AFE_3220
Hypothetical protein; Identified by glimmer; putative.
  
     0.752
AFE_0274
Disulfide bond formation protein B, putative; Identified by similarity to SP:P30018.
  
     0.725
AFE_3096
Conserved hypothetical protein; Identified by similarity to GB:AAQ58453.1.
  
     0.719
AFE_1855
Membrane protein, putative; Identified by match to protein family HMM PF07690.
  
     0.718
AFE_1695
Conjugal transfer protein; Identified by similarity to SP:P54915; match to protein family HMM PF03524.
  
     0.715
AFE_1615
DNA primase TraC; Identified by similarity to SP:P27189; match to protein family HMM PF08401.
  
     0.708
AFE_1978
Identified by match to protein family HMM TIGR01352.
  
     0.705
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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