Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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vapC-2Virulence-associated protein, putative; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (134 aa)    
Predicted Functional Partners:
AFE_0477
Virulence protein, putative; Identified by similarity to SP:Q05459; match to protein family HMM PF04014.
 
 
 0.988
AFE_2130
Virulence-associated protein, putative; Identified by similarity to SP:Q05459.
 
 
 0.930
AFE_2771
SpoVT/AbrB like domain protein.
 
 
 0.672
AFE_1361
Plasmid stability protein, putative; Identified by similarity to SP:P55510.
 
 
 
 0.538
vapC-3
Plasmid stability protein, putative; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.
  
     0.494
prfB
Peptide chain release factor 2, programmed frameshift; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
       0.490
thrC
Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
       0.443
AFE_0475
Conserved hypothetical protein; Identified by similarity to GB:AAQ60147.1.
       0.439
recJ
single-stranded-DNA-specific exonuclease RecJ; Identified by similarity to SP:P21893; match to protein family HMM PF01368.
       0.439
lysS
lysyl-tRNA synthetase; Identified by similarity to SP:P14825; match to protein family HMM PF00152; match to protein family HMM PF01336; match to protein family HMM TIGR00499; Belongs to the class-II aminoacyl-tRNA synthetase family.
       0.422
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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