STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AFE_0484DNA internalization-related competence protein ComEC/Rec2; Identified by match to protein family HMM PF03772; match to protein family HMM TIGR00360. (736 aa)    
Predicted Functional Partners:
comF
Competence protein; Identified by similarity to SP:P31773.
 
  
 0.865
AFE_0017
DNA processing protein DprA, putative; Identified by match to protein family HMM PF02481; match to protein family HMM TIGR00732.
 
  
 0.827
AFE_0482
Conserved hypothetical protein; Identified by similarity to PIR:B83271.
 
     0.711
AFE_0475
Conserved hypothetical protein; Identified by similarity to GB:AAQ60147.1.
 
     0.563
AFE_0486
Biopolymer transport protein, ExbD/TolR family; Identified by match to protein family HMM PF02472.
       0.545
AFE_0485
MotA/TolQ/ExbB proton channel family protein; Identified by match to protein family HMM PF01618.
       0.543
pilD
Type IV pilus prepilin peptidase PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
   
  
 0.534
pilC
Type IV pilus biogenesis protein PilC; Identified by similarity to SP:P45793; match to protein family HMM PF00482.
   
  
 0.512
recA
recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
  
 0.493
AFE_3220
Hypothetical protein; Identified by glimmer; putative.
 
     0.484
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.