Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_0496Bacterial transferase hexapeptide repeat protein. (198 aa)    
Predicted Functional Partners:
AFE_0287
Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.
    
 
 0.857
cbbS-2
Ribulose bisphosphate carboxylase, small subunit; Identified by match to protein family HMM PF00101.
    
 
 0.643
cbbS-1
Ribulose bisphosphate carboxylase, small subunit; Identified by match to protein family HMM PF00101.
    
 
 0.643
ccbL2
Ribulose bisphosphate carboxylase, large subunit 2; Identified by match to protein family HMM PF00016.
    
 
 0.592
cbbL-2
Ribulose bisphosphate carboxylase, large subunit; RuBisCO catalyzes two reactions: the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site; Belongs to the RuBisCO large chain family. Type I subfamily.
    
 
 0.592
cbbL2
Ribulose bisphosphate carboxylase, large subunit 2; Identified by match to protein family HMM PF00016; match to protein family HMM PF02493; match to protein family HMM PF02788; Belongs to the RuBisCO large chain family.
    
 
 0.592
cbbL-1
Ribulose bisphosphate carboxylase, large subunit; RuBisCO catalyzes two reactions: the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site; Belongs to the RuBisCO large chain family. Type I subfamily.
    
 
 0.592
AFE_0495
Hypothetical protein; Identified by glimmer; putative.
       0.503
AFE_3010
Polyketide synthase, type I, putative; Identified by similarity to GB:AAK26474.1; match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM PF08240; match to protein family HMM PF08659.
  
  
 0.448
pyrC-2
Dihydroorotase, multifunctional complex type; Identified by similarity to SP:P81006; match to protein family HMM PF01979; match to protein family HMM TIGR00857.
  
    0.425
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.