Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cysCSulfate adenylyltransferase, putative/adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. (557 aa)    
Predicted Functional Partners:
cysNC
Sulfate adenylate transferase, large subunit/adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
  
 
0.997
cysD-1
Sulfate adenylyltransferase, small subunit; Identified by match to protein family HMM PF01507; match to protein family HMM TIGR02039.
  
 0.996
cysD-2
Sulfate adenylyltransferase, small subunit; Identified by match to protein family HMM PF01507; match to protein family HMM TIGR02039.
  
 0.996
cysH
Adenylylsulfate reductase, thioredoxin dependent; Reduction of activated sulfate into sulfite.
 0.993
cysN
Sulfate adenylyltransferase, large subunit; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
 
 
 0.993
cysI
Sulfite reductase (NADPH) hemoprotein beta-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
  
 0.990
cysJ
Sulfite reductase (NADPH) flavoprotein, alpha component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.
  
  
 0.975
cobA
uroporphyrin-III C-methyltransferase; Identified by similarity to SP:P21631; match to protein family HMM PF00590; match to protein family HMM TIGR01469; Belongs to the precorrin methyltransferase family.
 
  
 0.966
AFE_1053
Conserved domain protein; Identified by similarity to GB:AAF69908.1; match to protein family HMM PF01507.
  
 
 0.962
AFE_1301
Hypothetical protein; Identified by glimmer; putative.
  
 
 0.962
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.