Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_0549Conserved hypothetical protein; Identified by similarity to PIR:E82325. (1210 aa)    
Predicted Functional Partners:
AFE_2072
Conserved domain protein.
  
     0.705
ftsQ
Cell division protein FtsQ; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily.
  
     0.702
lptD
Organic solvent tolerance protein, putative; Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane; Belongs to the LptD family.
  
     0.690
AFE_0168
Hypothetical protein; Identified by glimmer; putative.
  
     0.688
AFE_0475
Conserved hypothetical protein; Identified by similarity to GB:AAQ60147.1.
  
     0.671
smg
Smg family protein; Belongs to the Smg family.
  
     0.666
holA
DNA polymerase III, delta subunit; Identified by similarity to SP:P28630; match to protein family HMM PF06144; match to protein family HMM TIGR01128.
 
     0.648
bamE
Lipoprotein, SmpA/OmlA family; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
   
 0.646
AFE_2831
Hypothetical protein; Identified by glimmer; putative.
  
   
 0.632
AFE_0458
Rare lipoprotein B, putative; Identified by similarity to SP:P10101.
 
     0.625
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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