| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AFE_0566 | AFE_0567 | AFE_0566 | AFE_0567 | Endoribonuclease L-PSP, putative; Identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004. | Conserved hypothetical protein; Identified by similarity to GB:AAL95505.1. | 0.781 |
| AFE_0566 | fusA | AFE_0566 | AFE_0324 | Endoribonuclease L-PSP, putative; Identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004. | Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] | 0.582 |
| AFE_0566 | gmk | AFE_0566 | AFE_0563 | Endoribonuclease L-PSP, putative; Identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.612 |
| AFE_0566 | recG | AFE_0566 | AFE_0568 | Endoribonuclease L-PSP, putative; Identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004. | ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. | 0.799 |
| AFE_0566 | rpoZ | AFE_0566 | AFE_0564 | Endoribonuclease L-PSP, putative; Identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.616 |
| AFE_0566 | spoT | AFE_0566 | AFE_0565 | Endoribonuclease L-PSP, putative; Identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004. | Guanosine-3,5-bis(diphosphate) 3-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.763 |
| AFE_0567 | AFE_0566 | AFE_0567 | AFE_0566 | Conserved hypothetical protein; Identified by similarity to GB:AAL95505.1. | Endoribonuclease L-PSP, putative; Identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004. | 0.781 |
| AFE_0567 | gmk | AFE_0567 | AFE_0563 | Conserved hypothetical protein; Identified by similarity to GB:AAL95505.1. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.513 |
| AFE_0567 | recG | AFE_0567 | AFE_0568 | Conserved hypothetical protein; Identified by similarity to GB:AAL95505.1. | ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. | 0.783 |
| AFE_0567 | rpoZ | AFE_0567 | AFE_0564 | Conserved hypothetical protein; Identified by similarity to GB:AAL95505.1. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.564 |
| AFE_0567 | spoT | AFE_0567 | AFE_0565 | Conserved hypothetical protein; Identified by similarity to GB:AAL95505.1. | Guanosine-3,5-bis(diphosphate) 3-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.732 |
| AFE_0827 | AFE_3194 | AFE_0827 | AFE_3194 | ATP-dependent DNA helicase, putative; Identified by similarity to SP:O50224. | ATP-dependent DNA helicase RecG domain protein; Identified by similarity to SP:O50224; match to protein family HMM PF04326. | 0.929 |
| AFE_0827 | recG | AFE_0827 | AFE_0568 | ATP-dependent DNA helicase, putative; Identified by similarity to SP:O50224. | ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. | 0.900 |
| AFE_3194 | AFE_0827 | AFE_3194 | AFE_0827 | ATP-dependent DNA helicase RecG domain protein; Identified by similarity to SP:O50224; match to protein family HMM PF04326. | ATP-dependent DNA helicase, putative; Identified by similarity to SP:O50224. | 0.929 |
| AFE_3194 | recG | AFE_3194 | AFE_0568 | ATP-dependent DNA helicase RecG domain protein; Identified by similarity to SP:O50224; match to protein family HMM PF04326. | ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. | 0.900 |
| fusA | AFE_0566 | AFE_0324 | AFE_0566 | Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] | Endoribonuclease L-PSP, putative; Identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004. | 0.582 |
| fusA | gmk | AFE_0324 | AFE_0563 | Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.418 |
| fusA | lepA | AFE_0324 | AFE_1397 | Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.547 |
| fusA | pyrG | AFE_0324 | AFE_0847 | Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.755 |
| fusA | recG | AFE_0324 | AFE_0568 | Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] | ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. | 0.710 |
