Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_0569Identified by match to protein family HMM PF03734. (281 aa)    
Predicted Functional Partners:
AFE_2572
Identified by match to protein family HMM PF03734.
 
  
 0.782
AFE_0382
Identified by match to protein family HMM PF01476; match to protein family HMM PF03734.
 
  
 0.770
AFE_0998
Transcriptional regulator, putative; Identified by similarity to SP:Q06553; match to protein family HMM PF00717; match to protein family HMM PF01381; match to protein family HMM PF07022.
      
 0.723
AFE_1942
Hypothetical protein; Identified by glimmer; putative.
      
 0.723
AFE_1055
Hypothetical protein; Identified by glimmer; putative.
      
 0.722
AFE_1354
Glycosyl transferase, group 1 family protein; Identified by match to protein family HMM PF00534.
      
 0.722
AFE_2811
Lipoprotein, putative.
 
    0.634
dacB
D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; Identified by similarity to SP:P24228; match to protein family HMM PF02113; match to protein family HMM TIGR00666.
 
  
  0.587
AFE_2144
Penicillin-binding protein 2, putative; Identified by similarity to SP:P08150; match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM TIGR03423.
     
 0.550
mrdA
Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall.
     
 0.550
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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