Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_0577Membrane protein, putative; Identified by match to protein family HMM PF03706; match to protein family HMM TIGR00374. (359 aa)    
Predicted Functional Partners:
pabB
Para-aminobenzoate synthase, component I; Identified by similarity to SP:P05041; match to protein family HMM PF00425; match to protein family HMM PF04715; match to protein family HMM TIGR00553.
       0.773
AFE_0169
Conserved domain protein; Identified by similarity to GB:CAD74705.1.
  
     0.645
AFE_2896
Identified by match to protein family HMM PF04932.
 
     0.643
AFE_2325
Hypothetical protein; Identified by glimmer; putative.
  
     0.524
AFE_0575
Type I secretion outer membrane protein, TolC family; Identified by similarity to SP:P02930; match to protein family HMM PF02321; match to protein family HMM TIGR01844.
       0.515
AFE_0458
Rare lipoprotein B, putative; Identified by similarity to SP:P10101.
  
     0.467
AFE_0304
Conserved hypothetical protein; Identified by similarity to GB:AAM24168.1.
  
     0.466
AFE_3220
Hypothetical protein; Identified by glimmer; putative.
 
     0.463
AFE_0579
Hypothetical protein; Identified by glimmer; putative.
       0.435
AFE_0649
Identified by match to protein family HMM PF03372.
  
  
 0.429
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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