Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_0582Conserved hypothetical protein; Identified by similarity to GB:AAL62784.1. (65 aa)    
Predicted Functional Partners:
AFE_0583
Hypothetical protein; Identified by glimmer; putative.
       0.773
AFE_1367
Conserved hypothetical protein; Identified by similarity to PIR:AF2077; match to protein family HMM PF04255.
  
     0.549
AFE_1998
Hypothetical protein; Identified by glimmer; putative.
      
 0.460
AFE_0233
Glycosyl transferase, group 2 family protein; Identified by match to protein family HMM PF00535.
      
 0.456
AFE_1339
Polysaccharide biosynthesis/export domain protein; Identified by match to protein family HMM PF02563.
      
 0.450
AFE_2209
Transcriptional regulator, TetR family; Identified by match to protein family HMM PF00440.
      
 0.448
AFE_2641
Transcriptional regulator, ArsR family; Identified by match to protein family HMM PF01022.
      
 0.448
zwf
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
      
 0.445
AFE_2414
Conserved hypothetical protein; Identified by similarity to GB:AAN70104.1; match to protein family HMM PF04365.
  
     0.405
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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