Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_0620Hypothetical protein; Identified by glimmer; putative. (261 aa)    
Predicted Functional Partners:
AFE_2998
TonB-dependent receptor; Identified by match to protein family HMM PF00593; match to protein family HMM PF07715.
  
     0.752
AFE_3229
TonB-dependent receptor; Identified by match to protein family HMM PF00593; match to protein family HMM PF07715.
  
     0.743
AFE_0763
TonB-dependent receptor, putative; Identified by match to protein family HMM PF00593; match to protein family HMM PF07715.
  
     0.737
cyc2
Cytochrome c; Identified by similarity to GB:CAA07031.1.
  
     0.737
AFE_3115
Conserved hypothetical protein; Identified by similarity to SP:O67860.
  
     0.735
AFE_1428
Cytochrome c; Identified by similarity to GB:CAA07031.1.
  
     0.725
AFE_2935
TonB-dependent receptor; Identified by match to protein family HMM PF00593.
  
     0.723
AFE_0030
Hypothetical protein; Identified by glimmer; putative.
  
     0.701
AFE_0969
Type IV pilin, putative; Identified by match to protein family HMM TIGR02532.
  
     0.684
tetH
Tetrathionate hydrolase; Catalyzes the hydrolysis of tetrathionate to generate elemental sulfur, thiosulfate and sulfate.
  
     0.648
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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