Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AFE_0622Conserved hypothetical protein; Identified by similarity to GB:BAC65281.1. (270 aa)    
Predicted Functional Partners:
AFE_0623
Methyltransferase, UbiE/COQ5 family; Identified by match to protein family HMM PF01209; match to protein family HMM PF08241; match to protein family HMM PF08242.
 
     0.689
AFE_2014
Alkylhydroperoxidase AhpD family core domain protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.
  
    0.636
AFE_2011
Transcriptional regulator, TetR family; Identified by match to protein family HMM PF00440.
  
   
 0.519
AFE_2651
Copper resistance protein, putative; Identified by match to protein family HMM PF05425.
  
     0.515
AFE_2297
Identified by match to protein family HMM PF04185; match to protein family HMM TIGR01409.
  
     0.487
AFE_2013
Transcriptional regulator, MarR family; Identified by match to protein family HMM PF01047.
  
 
 
 0.473
AFE_0620
Hypothetical protein; Identified by glimmer; putative.
       0.465
leuC
3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
       0.458
AFE_2796
Transcriptional regulator, ArsR family.
  
    0.438
AFE_2005
Isonitrile hydratase, putative; Identified by similarity to GB:BAC41251.1; match to protein family HMM PF01965.
  
  
 0.428
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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