| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AFE_0227 | AFE_1956 | AFE_0227 | AFE_1956 | Mutator mutT protein/thiamine-phosphate pyrophosphorylase family protein; Identified by match to protein family HMM PF00293; match to protein family HMM PF02581; match to protein family HMM TIGR00586; Belongs to the Nudix hydrolase family. | Oxidoreductase, FAD-binding; Identified by match to protein family HMM PF01266. | 0.412 |
| AFE_0227 | AFE_3305 | AFE_0227 | AFE_3305 | Mutator mutT protein/thiamine-phosphate pyrophosphorylase family protein; Identified by match to protein family HMM PF00293; match to protein family HMM PF02581; match to protein family HMM TIGR00586; Belongs to the Nudix hydrolase family. | Phosphomethylpyrimidine kinase, putative; Identified by match to protein family HMM PF08543. | 0.879 |
| AFE_0227 | moeB | AFE_0227 | AFE_0652 | Mutator mutT protein/thiamine-phosphate pyrophosphorylase family protein; Identified by match to protein family HMM PF00293; match to protein family HMM PF02581; match to protein family HMM TIGR00586; Belongs to the Nudix hydrolase family. | Molybdopterin biosynthesis MoeB protein; Identified by similarity to SP:P12282; match to protein family HMM PF00899; match to protein family HMM PF05237. | 0.713 |
| AFE_0227 | thiC | AFE_0227 | AFE_0948 | Mutator mutT protein/thiamine-phosphate pyrophosphorylase family protein; Identified by match to protein family HMM PF00293; match to protein family HMM PF02581; match to protein family HMM TIGR00586; Belongs to the Nudix hydrolase family. | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.877 |
| AFE_0227 | thiG | AFE_0227 | AFE_0643 | Mutator mutT protein/thiamine-phosphate pyrophosphorylase family protein; Identified by match to protein family HMM PF00293; match to protein family HMM PF02581; match to protein family HMM TIGR00586; Belongs to the Nudix hydrolase family. | Thiamin biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.907 |
| AFE_0227 | thiS | AFE_0227 | AFE_0642 | Mutator mutT protein/thiamine-phosphate pyrophosphorylase family protein; Identified by match to protein family HMM PF00293; match to protein family HMM PF02581; match to protein family HMM TIGR00586; Belongs to the Nudix hydrolase family. | Thiamine biosynthesis protein ThiS; Identified by match to protein family HMM PF02597; match to protein family HMM TIGR01683. | 0.904 |
| AFE_0644 | mpl | AFE_0644 | AFE_0645 | Hypothetical protein; Identified by glimmer; putative. | UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. | 0.787 |
| AFE_0644 | thiG | AFE_0644 | AFE_0643 | Hypothetical protein; Identified by glimmer; putative. | Thiamin biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.805 |
| AFE_0644 | thiS | AFE_0644 | AFE_0642 | Hypothetical protein; Identified by glimmer; putative. | Thiamine biosynthesis protein ThiS; Identified by match to protein family HMM PF02597; match to protein family HMM TIGR01683. | 0.642 |
| AFE_1956 | AFE_0227 | AFE_1956 | AFE_0227 | Oxidoreductase, FAD-binding; Identified by match to protein family HMM PF01266. | Mutator mutT protein/thiamine-phosphate pyrophosphorylase family protein; Identified by match to protein family HMM PF00293; match to protein family HMM PF02581; match to protein family HMM TIGR00586; Belongs to the Nudix hydrolase family. | 0.412 |
| AFE_1956 | thiG | AFE_1956 | AFE_0643 | Oxidoreductase, FAD-binding; Identified by match to protein family HMM PF01266. | Thiamin biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.995 |
| AFE_1956 | thiS | AFE_1956 | AFE_0642 | Oxidoreductase, FAD-binding; Identified by match to protein family HMM PF01266. | Thiamine biosynthesis protein ThiS; Identified by match to protein family HMM PF02597; match to protein family HMM TIGR01683. | 0.652 |
| AFE_3305 | AFE_0227 | AFE_3305 | AFE_0227 | Phosphomethylpyrimidine kinase, putative; Identified by match to protein family HMM PF08543. | Mutator mutT protein/thiamine-phosphate pyrophosphorylase family protein; Identified by match to protein family HMM PF00293; match to protein family HMM PF02581; match to protein family HMM TIGR00586; Belongs to the Nudix hydrolase family. | 0.879 |
| AFE_3305 | moeB | AFE_3305 | AFE_0652 | Phosphomethylpyrimidine kinase, putative; Identified by match to protein family HMM PF08543. | Molybdopterin biosynthesis MoeB protein; Identified by similarity to SP:P12282; match to protein family HMM PF00899; match to protein family HMM PF05237. | 0.852 |
| AFE_3305 | thiC | AFE_3305 | AFE_0948 | Phosphomethylpyrimidine kinase, putative; Identified by match to protein family HMM PF08543. | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.991 |
| AFE_3305 | thiE | AFE_3305 | AFE_3304 | Phosphomethylpyrimidine kinase, putative; Identified by match to protein family HMM PF08543. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.999 |
| AFE_3305 | thiG | AFE_3305 | AFE_0643 | Phosphomethylpyrimidine kinase, putative; Identified by match to protein family HMM PF08543. | Thiamin biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.943 |
| AFE_3305 | thiS | AFE_3305 | AFE_0642 | Phosphomethylpyrimidine kinase, putative; Identified by match to protein family HMM PF08543. | Thiamine biosynthesis protein ThiS; Identified by match to protein family HMM PF02597; match to protein family HMM TIGR01683. | 0.869 |
| dxs | thiG | AFE_1974 | AFE_0643 | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | Thiamin biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.930 |
| moeB | AFE_0227 | AFE_0652 | AFE_0227 | Molybdopterin biosynthesis MoeB protein; Identified by similarity to SP:P12282; match to protein family HMM PF00899; match to protein family HMM PF05237. | Mutator mutT protein/thiamine-phosphate pyrophosphorylase family protein; Identified by match to protein family HMM PF00293; match to protein family HMM PF02581; match to protein family HMM TIGR00586; Belongs to the Nudix hydrolase family. | 0.713 |
