Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_0649Identified by match to protein family HMM PF03372. (250 aa)    
Predicted Functional Partners:
moeB
Molybdopterin biosynthesis MoeB protein; Identified by similarity to SP:P12282; match to protein family HMM PF00899; match to protein family HMM PF05237.
       0.749
AFE_0651
Hypothetical protein; Identified by glimmer; putative.
       0.742
AFE_0654
ABC transporter, permease protein; Identified by match to protein family HMM PF02687.
 
     0.597
AFE_2212
Conserved hypothetical protein; Identified by similarity to GB:AAM38230.1.
  
     0.579
AFE_1088
Thiol:disulfide interchange protein, DsbA family; Identified by similarity to SP:Q44504.
 
    0.532
AFE_0653
Conserved hypothetical protein; Identified by similarity to GB:CAD85317.1.
       0.494
AFE_0655
ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005.
       0.494
ftsL
Cell division protein FtsL; Essential cell division protein; Belongs to the FtsL family.
  
     0.480
AFE_0166
HNH endonuclease domain protein; Identified by match to protein family HMM PF01844.
  
     0.441
AFE_0577
Membrane protein, putative; Identified by match to protein family HMM PF03706; match to protein family HMM TIGR00374.
  
  
 0.429
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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