Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_0653Conserved hypothetical protein; Identified by similarity to GB:CAD85317.1. (408 aa)    
Predicted Functional Partners:
AFE_0654
ABC transporter, permease protein; Identified by match to protein family HMM PF02687.
     0.976
AFE_0655
ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005.
 
   
 0.859
moeB
Molybdopterin biosynthesis MoeB protein; Identified by similarity to SP:P12282; match to protein family HMM PF00899; match to protein family HMM PF05237.
 
     0.577
AFE_0649
Identified by match to protein family HMM PF03372.
       0.494
AFE_0651
Hypothetical protein; Identified by glimmer; putative.
       0.488
AFE_1109
Conserved domain protein; Identified by similarity to GB:BAC41664.1; match to protein family HMM PF08378.
  
     0.451
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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