Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
AFE_0654ABC transporter, permease protein; Identified by match to protein family HMM PF02687. (835 aa)    
Predicted Functional Partners:
AFE_0655
ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005.
 
 
 0.997
AFE_0101
ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005.
  
 
 0.987
lolD
Lipoprotein releasing system, ATP-binding protein LolD; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
  
 
 0.987
AFE_0653
Conserved hypothetical protein; Identified by similarity to GB:CAD85317.1.
     0.976
AFE_0164
S4 domain protein; Identified by match to protein family HMM PF01479.
   
    0.755
gpsA
Glycerol-3-phosphate dehydrogenase (NAD(P)+); Identified by similarity to SP:P37606; match to protein family HMM PF01210; match to protein family HMM PF07479; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
  
  
 0.753
AFE_1144
Dihydroorotate dehydrogenase domain protein, putative; Identified by similarity to SP:Q8XYY7.
      
 0.724
AFE_1143
Hypothetical protein; Identified by glimmer; putative.
      
 0.722
cysE-2
Serine O-acetyltransferase; Identified by similarity to SP:Q06750; match to protein family HMM PF00132; match to protein family HMM TIGR01172.
      
 0.720
AFE_0109
Efflux transporter, RND family, MFP subunit; Identified by match to protein family HMM PF00529; match to protein family HMM TIGR01730; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 
 0.715
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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