Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_0665Identified by match to protein family HMM PF01722; Belongs to the BolA/IbaG family. (103 aa)    
Predicted Functional Partners:
AFE_3038
Identified by match to protein family HMM PF00462; match to protein family HMM TIGR00365; Belongs to the glutaredoxin family. Monothiol subfamily.
 
 
 0.921
AFE_0666
YCII-related domain protein; Identified by match to protein family HMM PF03795.
       0.805
argA
N-acetylglutamate synthase; Identified by similarity to SP:P08205; match to protein family HMM PF00583; match to protein family HMM PF00696; match to protein family HMM TIGR01890; Belongs to the acetyltransferase family. ArgA subfamily.
  
    0.779
ispZ
Intracellular septation protein A; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family.
 
    0.743
AFE_0668
Conserved hypothetical protein; Identified by similarity to GB:CAD86126.1; match to protein family HMM PF05673.
 
     0.521
AFE_1508
Nitrogen fixation protein nifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.
   
 
 0.455
AFE_3037
Identified by match to protein family HMM PF01722; Belongs to the BolA/IbaG family.
 
   
 0.451
AFE_3010
Polyketide synthase, type I, putative; Identified by similarity to GB:AAK26474.1; match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM PF08240; match to protein family HMM PF08659.
   
 
 0.409
petC-2
Ubiquinol--cytochrome c reductase, cytochrome c1 subunit; Identified by match to protein family HMM PF02167.
  
    0.408
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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