Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AFE_0666YCII-related domain protein; Identified by match to protein family HMM PF03795. (109 aa)    
Predicted Functional Partners:
AFE_0665
Identified by match to protein family HMM PF01722; Belongs to the BolA/IbaG family.
       0.805
argA
N-acetylglutamate synthase; Identified by similarity to SP:P08205; match to protein family HMM PF00583; match to protein family HMM PF00696; match to protein family HMM TIGR01890; Belongs to the acetyltransferase family. ArgA subfamily.
 
     0.804
ispZ
Intracellular septation protein A; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family.
  
    0.661
AFE_2564
Rod shape-determining protein MreD, putative; Identified by similarity to SP:P16927; match to protein family HMM TIGR03426.
  
     0.640
sdr_1
Oxidoreductase, short-chain dehydrogenase/reductase family; Identified by match to protein family HMM PF00106; match to protein family HMM PF08659.
  
    0.576
recX
Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family.
  
     0.551
AFE_1978
Identified by match to protein family HMM TIGR01352.
 
    0.541
hflD
Conserved hypothetical protein; Identified by similarity to GB:AAM85366.1.
  
    0.511
folB
Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
  
     0.473
AFE_0668
Conserved hypothetical protein; Identified by similarity to GB:CAD86126.1; match to protein family HMM PF05673.
       0.446
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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