Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AFE_0720FAD-dependent oxidoreductase; Identified by match to protein family HMM PF01266. (416 aa)    
Predicted Functional Partners:
gcvT
Glycine cleavage system T protein; Identified by match to protein family HMM PF01571; match to protein family HMM PF08669; match to protein family HMM TIGR00528.
  
 
 0.729
AFE_2601
Pyridine nucleotide-disulfide oxidoreductase; Identified by similarity to SP:Q9R112; match to protein family HMM PF07992.
   
 
 0.651
AFE_3118
Pyridine nucleotide-disulfide oxidoreductase; Identified by similarity to SP:Q9R112; match to protein family HMM PF07992.
   
 
 0.651
AFE_2148
DNA-binding protein, putative; Identified by similarity to GB:AAO56394.1; match to protein family HMM PF01381; match to protein family HMM PF07883.
 
  
 0.616
AFE_0719
Amino acid permease family protein; Identified by match to protein family HMM PF00324.
       0.584
AFE_0721
Conserved hypothetical protein; Identified by similarity to PIR:A97389.
       0.547
hypB-1
Hydrogenase accessory protein HypB; Identified by similarity to SP:P24190; match to protein family HMM PF02492; match to protein family HMM TIGR00073.
       0.523
gltB
Glutamate synthase, large subunit; Identified by similarity to SP:P09831; match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898.
  
  
 0.458
AFE_3010
Polyketide synthase, type I, putative; Identified by similarity to GB:AAK26474.1; match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM PF08240; match to protein family HMM PF08659.
  
 
 0.453
AFE_2776
Benzoylformate decarboxylase; Identified by similarity to SP:P20906; match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family.
  
  
 0.435
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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