Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AFE_0740Hypothetical protein; Identified by glimmer; putative. (56 aa)    
Predicted Functional Partners:
tadA-2
Cytidine and deoxycytidylate deaminase family protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
       0.752
AFE_0742
Conserved hypothetical protein TIGR00149; Identified by match to protein family HMM PF01894; match to protein family HMM TIGR00149.
       0.752
AFE_0743
Conserved domain protein.
       0.752
AFE_0744
MutS domain V protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity. Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
       0.570
AFE_0736
Type 4 fimbrial biogenesis protein PilP, putative; Identified by similarity to GB:AAA93089.1.
       0.561
AFE_0737
Fimbrial assembly protein PilO, putative; Identified by match to protein family HMM PF04350.
       0.561
AFE_0738
Type IV pilus biogenesis protein PilN; Identified by match to protein family HMM PF05137.
       0.561
AFE_0739
Type IV pilus assembly protein PilM; Identified by similarity to PIR:S77726; match to protein family HMM TIGR01175.
       0.561
aroK
Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
       0.468
AFE_0735
Fimbrial assembly protein PilQ, putative; Identified by similarity to SP:P34750; match to protein family HMM PF00263; match to protein family HMM PF03958; match to protein family HMM PF07660; match to protein family HMM TIGR02515.
       0.468
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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