Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
tadA-2Cytidine and deoxycytidylate deaminase family protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (177 aa)    
Predicted Functional Partners:
hisIE
phosphoribosyl-AMP pyrophosphatase/phosphoribosyl-ATP cyclohydrolase; Identified by similarity to SP:O34912; match to protein family HMM PF01502; match to protein family HMM PF01503; match to protein family HMM TIGR03188; match to protein family HMM TIGR03456; In the N-terminal section; belongs to the PRA-CH family.
   
  
 0.939
AFE_0742
Conserved hypothetical protein TIGR00149; Identified by match to protein family HMM PF01894; match to protein family HMM TIGR00149.
       0.789
AFE_0743
Conserved domain protein.
       0.783
AFE_0740
Hypothetical protein; Identified by glimmer; putative.
       0.752
AFE_1466
HAD-superfamily hydrolase, subfamily IA, variant 3; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509.
 
      0.701
AFE_0744
MutS domain V protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity. Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
     
 0.647
tilS
tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.
  
 0.588
AFE_3079
Identified by match to protein family HMM PF00881.
  
  
 0.567
rsmI
Tetrapyrrole methylase family protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
 
  
 0.564
birA
birA bifunctional protein; Identified by match to protein family HMM PF02237; match to protein family HMM PF03099; match to protein family HMM TIGR00121.
  
    0.554
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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