node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AFE_0756 | AFE_0759 | AFE_0756 | AFE_0759 | HAD-superfamily subfamily IB hydrolase, TIGR01490; Identified by similarity to GB:AAN70712.1; match to protein family HMM PF00702; match to protein family HMM TIGR01488; match to protein family HMM TIGR01490. | Methyltransferase, putative; Identified by match to protein family HMM PF08241; match to protein family HMM PF08242. | 0.539 |
AFE_0756 | atpC-2 | AFE_0756 | AFE_0758 | HAD-superfamily subfamily IB hydrolase, TIGR01490; Identified by similarity to GB:AAN70712.1; match to protein family HMM PF00702; match to protein family HMM TIGR01488; match to protein family HMM TIGR01490. | ATP synthase F1, epsilon subunit, putative; Produces ATP from ADP in the presence of a proton gradient across the membrane. | 0.545 |
AFE_0756 | ligA | AFE_0756 | AFE_0757 | HAD-superfamily subfamily IB hydrolase, TIGR01490; Identified by similarity to GB:AAN70712.1; match to protein family HMM PF00702; match to protein family HMM TIGR01488; match to protein family HMM TIGR01490. | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | 0.546 |
AFE_0759 | AFE_0756 | AFE_0759 | AFE_0756 | Methyltransferase, putative; Identified by match to protein family HMM PF08241; match to protein family HMM PF08242. | HAD-superfamily subfamily IB hydrolase, TIGR01490; Identified by similarity to GB:AAN70712.1; match to protein family HMM PF00702; match to protein family HMM TIGR01488; match to protein family HMM TIGR01490. | 0.539 |
AFE_0759 | atpC-2 | AFE_0759 | AFE_0758 | Methyltransferase, putative; Identified by match to protein family HMM PF08241; match to protein family HMM PF08242. | ATP synthase F1, epsilon subunit, putative; Produces ATP from ADP in the presence of a proton gradient across the membrane. | 0.765 |
AFE_0759 | ligA | AFE_0759 | AFE_0757 | Methyltransferase, putative; Identified by match to protein family HMM PF08241; match to protein family HMM PF08242. | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | 0.728 |
atpC-2 | AFE_0756 | AFE_0758 | AFE_0756 | ATP synthase F1, epsilon subunit, putative; Produces ATP from ADP in the presence of a proton gradient across the membrane. | HAD-superfamily subfamily IB hydrolase, TIGR01490; Identified by similarity to GB:AAN70712.1; match to protein family HMM PF00702; match to protein family HMM TIGR01488; match to protein family HMM TIGR01490. | 0.545 |
atpC-2 | AFE_0759 | AFE_0758 | AFE_0759 | ATP synthase F1, epsilon subunit, putative; Produces ATP from ADP in the presence of a proton gradient across the membrane. | Methyltransferase, putative; Identified by match to protein family HMM PF08241; match to protein family HMM PF08242. | 0.765 |
atpC-2 | ligA | AFE_0758 | AFE_0757 | ATP synthase F1, epsilon subunit, putative; Produces ATP from ADP in the presence of a proton gradient across the membrane. | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | 0.800 |
leuS | ligA | AFE_0459 | AFE_0757 | leucyl-tRNA synthetase; Identified by similarity to SP:P07813; match to protein family HMM PF00133; match to protein family HMM PF08264; match to protein family HMM PF09334; match to protein family HMM TIGR00396; Belongs to the class-I aminoacyl-tRNA synthetase family. | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | 0.673 |
leuS | ligA-2 | AFE_0459 | AFE_1230 | leucyl-tRNA synthetase; Identified by similarity to SP:P07813; match to protein family HMM PF00133; match to protein family HMM PF08264; match to protein family HMM PF09334; match to protein family HMM TIGR00396; Belongs to the class-I aminoacyl-tRNA synthetase family. | DNA ligase, NAD-dependent, putative; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | 0.660 |
leuS | polI | AFE_0459 | AFE_3094 | leucyl-tRNA synthetase; Identified by similarity to SP:P07813; match to protein family HMM PF00133; match to protein family HMM PF08264; match to protein family HMM PF09334; match to protein family HMM TIGR00396; Belongs to the class-I aminoacyl-tRNA synthetase family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.488 |
leuS | topA | AFE_0459 | AFE_0015 | leucyl-tRNA synthetase; Identified by similarity to SP:P07813; match to protein family HMM PF00133; match to protein family HMM PF08264; match to protein family HMM PF09334; match to protein family HMM TIGR00396; Belongs to the class-I aminoacyl-tRNA synthetase family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.994 |
ligA | AFE_0756 | AFE_0757 | AFE_0756 | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | HAD-superfamily subfamily IB hydrolase, TIGR01490; Identified by similarity to GB:AAN70712.1; match to protein family HMM PF00702; match to protein family HMM TIGR01488; match to protein family HMM TIGR01490. | 0.546 |
ligA | AFE_0759 | AFE_0757 | AFE_0759 | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | Methyltransferase, putative; Identified by match to protein family HMM PF08241; match to protein family HMM PF08242. | 0.728 |
ligA | atpC-2 | AFE_0757 | AFE_0758 | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | ATP synthase F1, epsilon subunit, putative; Produces ATP from ADP in the presence of a proton gradient across the membrane. | 0.800 |
ligA | leuS | AFE_0757 | AFE_0459 | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | leucyl-tRNA synthetase; Identified by similarity to SP:P07813; match to protein family HMM PF00133; match to protein family HMM PF08264; match to protein family HMM PF09334; match to protein family HMM TIGR00396; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.673 |
ligA | ligA-2 | AFE_0757 | AFE_1230 | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | DNA ligase, NAD-dependent, putative; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | 0.925 |
ligA | polI | AFE_0757 | AFE_3094 | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.582 |
ligA | ruvB | AFE_0757 | AFE_0062 | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.547 |